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The majority of the pages did not implement safeguarding measures to prevent users aged under 18 from accessing the pages, with 56 per cent of the brand-sponsored pages and 90 per cent of online vendors failing to filter out younger customers

Restricted cubic spline functions were employed to investigate the doseresponse non-linear relationship

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Data gathered by Northeastern University provided the following list: Maine, New Jersey and Oregon require that a person be 21 to purchase e-cigarette products Hawaii requires the age of 21 for sale, distribution and use of e-cigarettes California requires that a person be 21 to purchase both e-cigarettes and conventional cigarettes Alaska, Utah and Alabama require the age of 19 to buy and possess e-cigarettes and related products The remaining 42 states only require a person to be 18 to purchase e-cigarettes In most cases, changes in tobacco laws have also affected vaping, although lawmakers, medical experts and public health officials do not agree on the safety of e-cigarettes